The Gastrointestinal Oncology Translational Lab (PI, Manish A Shah MD) is focused on advancing our understanding of gastrointestinal malignancies to improve patient care. We use the latest tools to better characterize disease and the substrate it lies in to understand drivers of treatment resistance and how they may be leveraged to improve therapeutic efficacy.
The Lab Team
The Shah lab welcomes a diverse set of talents and fosters an interdisciplinary approach in its attempts to translate fundamental scientific discoveries into clinical innovations.
Our Research
The Shah lab's mission is to investigate mechanisms of resistance to novel therapies. This includes examining the tumor microenvironment, comprehensive molecular annotation, and development of preclinical examine potential mechanisms of action.